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Dong Quai

Dong Quai

Angelica Sinensis (Oliv. ) Diels
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Common Name

Dong quai,

Chinese angelica,

toki (Japanese),

tanggwi (Korean),

tang-kuei (Taiwanese)

Family

Apiaceae

Parts Used

Root

Native To

Endemic to China (Leon & Yu-Lin, 2017), the plant thrives in the cool, shady mountain woods found in the southern and western region of the country (Kuhn & Winston, 2005).

Historical and Traditional Uses

  • Traditional Chinese Medicine (TCM): Used for over 2,000 years to nourish the blood, balance hormones, and treat menstrual irregularities.
  • Women’s Health: Known as the "female ginseng," it is used to alleviate menopausal symptoms, regulate menstruation, and enhance fertility.
  • Other Uses: Applied as a general tonic to improve circulation, reduce inflammation, and combat fatigue.

Chemical Composition

  • Coumarins: Umbelliferone, psoralen (anticoagulant and vascular health properties).
  • Phthalides: Ligustilide, butylidenephthalide (relieves smooth muscle spasms and improves blood flow).
  • Polysaccharides: Enhance immune function.
  • Essential Oils: Beta-caryophyllene, ferulic acid (anti-inflammatory and antioxidant properties).
  • Vitamins and Minerals: Vitamin B12, iron, folic acid (support blood health).

Pharmacological Properties

  • Hormonal Balancer: Regulates estrogen levels by acting as a phytoestrogen.
  • Blood Circulation Enhancer: Improves microcirculation and prevents clot formation.
  • Anti-inflammatory: Reduces inflammation and oxidative stress in tissues.
  • Smooth Muscle Relaxant: Relieves uterine cramps and gastrointestinal spasms.
  • Immune Modulator: Supports immune system function.
  • Cardioprotective: Improves cardiovascular health by promoting healthy blood flow.

Evidence-Based Uses and Benefits

  1. Relieves Menstrual Disorders:
  • Effect: Alleviates cramps, irregular periods, and heavy bleeding.
  • Key Study: Clinical trials show that Dong Quai is effective in reducing dysmenorrhea (painful menstruation)
  1. Supports Menopause Management:
  • Use: Reduces symptoms like hot flashes, night sweats, and mood swings.
  • Evidence: Works synergistically with other herbs like black cohosh and red clover for menopausal support.
  1. Improves Circulation:
  • Mechanism: Enhances blood flow, reducing symptoms of anemia and cold extremities.
  1. Boosts Fertility:
  • Effect: Nourishes the blood and regulates hormones, improving reproductive health.
  1. Anti-inflammatory and Antioxidant:
  • Use: Reduces chronic inflammation, particularly in conditions like arthritis.
  1. Supports Cardiovascular Health:
  • Mechanism: Prevents blood clot formation and reduces hypertension.

Counter-Indications

  • Pregnancy: Avoid due to potential uterine-stimulating effects, which could lead to miscarriage.
  • Bleeding Disorders: Dong Quai may increase bleeding risk.
  • Hormone-Sensitive Conditions: Avoid if you have estrogen-dependent cancers, such as breast or uterine cancer.

Side Effects

  • Mild gastrointestinal discomfort, including bloating or nausea.
  • Photosensitivity, causing skin reactions in sunlight.
  • Rare cases of headaches or dizziness.

Drug Interactions

  • Anticoagulants and Antiplatelet Drugs: May increase bleeding risk (e.g., warfarin, aspirin).
  • Hormonal Therapies: May interact with estrogen replacement therapy.
  • Blood Pressure Medications: May enhance the effects of antihypertensive drugs.
  • Herbs: Synergizes well with black cohosh and red clover for hormonal support.

Conclusion

Dong Quai is a versatile herb with significant benefits for women’s health, cardiovascular support, and inflammation management. Its phytoestrogenic and blood-enhancing properties make it a valuable tool for managing menstrual disorders, menopause symptoms, and poor circulation. However, it should be used cautiously in individuals with bleeding disorders or hormone-sensitive conditions.

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