Licorice Root

Traditional Chinese Medicine (TCM) Used as a harmonizer in herbal formulas, soothing coughs, and treating gastrointestinal issues. In Ayurveda it is known as Yashtimadhu, used for its rejuvenating, anti-inflammatory, and expectorant properties. Folk Medicine Commonly utilized for sore throat, ulcers, and as a natural sweetener

• Triterpenoid Saponins: Glycyrrhizin (key bioactive compound)
• Flavonoids: Liquiritin, isoliquiritigenin
• Coumarins: Herniarin, umbelliferone
• Polysaccharides: Arabinogalactans
• Other: Essential oils, tannins, and amino acids

• Anti-inflammatory: Reduces inflammation in the respiratory and digestive systems.
• Antiviral: Inhibits viral replication and boosts immunity.
• Expectorant: Clears mucus and soothes respiratory conditions.
• Hepatoprotective: Protects liver cells and supports detoxification.
• Adaptogenic: Reduces stress by regulating cortisol levels.
• Antioxidant: Neutralizes free radicals, preventing oxidative stress.
• Anti-ulcerative: Promotes healing of gastric ulcers and soothes the gut lining.

1. Respiratory Health:

• Use: Soothes sore throat, reduces coughing, and clears mucus.
• Study Reference: Wang et al., 2015 demonstrated antiviral activity against respiratory viruses.

2. Digestive Health:

• Effect: Treats gastric ulcers, acid reflux, and indigestion.
• Key Study: Akhondzadeh et al., 2009 confirmed its anti-ulcerative properties in clinical trials.

3. Immune System Support:

• Mechanism: Enhances immune response and inhibits viral replication.
• Research Insight: Studies support its role in managing hepatitis and other viral infections.

4. Stress and Adrenal Support:

• Effect: Modulates cortisol and improves adrenal function during stress.
• Evidence: Proven adaptogenic effects in preclinical and clinical studies.

5. Skin Health:

• Use: May also Treat eczema, psoriasis, and inflammation due to its anti-inflammatory and soothing properties.
• Clinical Insight: Topical formulations have shown significant benefits in reducing redness and irritation.

• High blood pressure (can cause water retention and increase sodium levels).
• Pregnancy (may affect hormonal balance and lead to uterine contractions).
• Kidney or heart conditions (risk of electrolyte imbalance).

• Potential for elevated blood pressure and water retention with excessive use.
• Hypokalemia (low potassium levels) if taken in high doses for prolonged periods.
• Rare cases of allergic reactions, including skin rash or itching.

• Corticosteroids: May enhance their effects, leading to higher cortisol levels.
• Diuretics: Can increase the risk of hypokalemia.
• Blood Pressure Medications: May counteract the effects of antihypertensive drugs.
• Hormonal Therapies: May influence estrogen and testosterone metabolism.

1. Antiviral Activity Licorice respiratory health: (https://pmc.ncbi.nlm.nih.gov/articles/PMC8703329/)
2. Digestive Health Effect on gastric ulcers:(https://pmc.ncbi.nlm.nih.gov/articles/PMC3818629/)
3. Immune Modulation hepatitis management:(https://pmc.ncbi.nlm.nih.gov/articles/PMC4052927/)

Licorice root extract (Glycyrrhiza glabra) is a versatile herbal remedy with significant benefits for respiratory health, digestive support, and immune enhancement. Its anti-inflammatory, adaptogenic, and hepatoprotective properties make it a valuable addition to herbal medicine. However, it should be used cautiously in individuals with high blood pressure or kidney conditions.